Res’vine® is a dried grape skin extract (from Vitis vinifera L.) containing a well-known polyphenol widely studied : resveratrol.
Historically, resveratrol research began in the 1990s with the discovery of the “French Paradox” concept. Indeed, the French population have less risk to have a cardiovascular disease compared to other countries while it consumes more animal fat and saturated fat. Strange paradox ! In reality, this beneficial effect is explained by the daily consumption of red wine among the French which contains the incredible molecule of resveratrol. Since then, numerous effects of resveratrol have been highlighted in scientific studies on the cardiovascular axis1, skin protection2, its antioxidant role3 and the cognitive axis4.
The health claim « For cardiovascular health » can be used for food supplement with 10 mg/day of resveratrol.
Dosage : no specific recommendation. Most food supplements contain between 250 to 500 mg/day of resveratrol
Properties of Res’Vine®
- More than 5% of trans-resveratrol (antioxidant action 7 times higher than the cis form)
- 100% from grape skin (main source of resveratrol)
- Excellent bioavailability
- Tomé-Carneiro J., Gonzalvez M., Larrosa M., Garcia-Almagro F.J. et al. Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial. Mol Nutr Food Res,2012;56:810-821
- Bastianetto S, Dumont Y, Duranton A, Vercauteren F, Breton L, Quirion R (2010) Protective Action of Resveratrol in Human Skin: Possible Involvement of Specific Receptor Binding Sites. PLoS ONE 5(9): e12935. doi:10.1371/journal.pone.0012935
- Nakata R, Takahashi S, Inoue H. 2012. Recent advances in the study on resveratrol. Biol. Pharm. Bull. 35: 273-9
- Witte A.V., Kerti L., Margulies D.S., and Flöel A. Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults. J Neurosci,2014;34(23):7862-7870.
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