NEW – NATTIASE® (Nattokinase)

Nattiase : a unique and innovative product

Every day, our cardiovascular system performs a mammoth task so that our blood travels 100,000 kilometres of blood vessels distributed throughout our body. Blood is a vital liquid. Its main role is to provide oxygen and nutrients in our organs and remove waste products (CO2) through the kidneys, lungs, liver or intestines. This cycle is repeated infinitely thanks to the blood circulation in one direction and continuous way. Bodily injury (cuts or internal injuries) can cause bleeding in our vessels. Fortunately, our body is able to neutralize them naturally thanks to the phenomenon of coagulation. Platelets come first to plug the injury and then fibrin (protein) intervenes. This reinforces coagulation by creating a protective net to form a blood clot. When the injured blood vessel heals, the plasmin goes into action to degrade the clot formed. This enzyme is a protease whose role is to degrade fibrin. However, when the coagulation phenomenon becomes abnormal, our body has difficulties dissolving blood clots especially due to certain risk factors (aging, sedentary lifestyle, smoking, diabetes, hypertension …). Indeed, plasmin level becomes lower and in parallel, fibrin level increases. If blood clots are not destroyed at the end of healing, they can completely clog a vessel and cause cardiovascular complications (World’s leading cause of death worldwide according WHO). The emergence of an atheroma plaque on an arterial wall that breaks can also cause a clot formation that preventing the smooth flow of blood.

Nattiase contains a fibrinolytic enzyme called nattokinase. It comes from natto, a soy-based food obtained by fermentation with the bacterium Bacillus subtilis.

An emblem and national treasure of Japan, natto has been consumed for more than 1000 years for its taste and nutritional composition. Much more than a simple dish, natto is considered as a traditional remedy for cardiovascular disease and would also contribute to Japanese longevity. This may be one of the reasons why the Japanese have better cardiovascular health compared to other countries.

In 1987, Dr. Hiroyuki Sumi discovers that natto contains a potent fibrinolytic enzyme called nattokinase. This plays a major role in the dissolution of blood clots that may form following the rupture of an atheromatous plaque (lipid deposition on the vessel wall).

Following the discovery of nattokinase, many studies have shown that its consumption has multiple preventive effects on cardiovascular diseases through its fibrinolytic action : decreased blood pressure, anticoagulant/anti-atherosclerosis/lipid-lowering effect.

Nattiase presents a real innovative alternative for the cardiovascular axis

  • Complies with the Novel Food regulation (Regulation 2015/2283)
  • Maximum dose : 100 mg/d of nattokinase corresponding to the reference dose approved by EFSA (2000 FU/d)
  • Dosage : 20000-28000 FU/g
  • Applications : food supplements in capsules, tablets or powder form for the cardiovascular axis

All of our references


To learn more, contact us !

Contact EN