Annurtrofil®: ideas for formulations and dosage forms.
One of the strengths of this ingredient is its versatility. It can be adapted to different galenic forms such as capsules, sachets or even liquid versions(water-soluble ).
Hair health
In this context, a capsule formula combined with Zinc and Selenium would be beneficial. For an effective daily intake, it would be preferable to integrate, for 2 or 3 capsules, 800mg/d of Annurtrofil®, 10mg/d of Zinc and 55 µg/d of Selenium, thus covering the total daily requirement of these two elements.
Zinc
Zinc helps maintain normal hair. It is involved in the physiological functioning of over 200 enzymes: mainly those involved in the fight against oxidative stress and therefore free radicals. But also those involved in protein biosynthesis and cell renewal processes8.
Selenium
Selenium also plays an important role in maintaining normal hair. Like Zinc, it is essential for the proper functioning of certain antioxidant enzymes8 and is involved in the synthesis of 35 proteins9.
Skin health
For skin health, a sachet formula would be interesting. According to existing clinical data, for an effective daily intake with a sachet, you need: 800mg/d of Annurtrofil®, type I marine collagen 4&5 (5000mg/d), ceramide 6&7 (30mg/d), vitamin C (80mg/d), zinc (10mg/d), selenium (55 µg/d) and biotin (50 µg/d)./p>
Type I fish collagen
Type I marine collagen helps improve skin elasticity and hydration. In fact, collagen hydrolysis is mainly composed of peptides called Proline-Hydroxyproline (PRO-HYP). These confer rigidity to the collagen molecule. Once ingested, these peptides pass through the intestinal mucosa and then participate in the formation of the epidermis, helping to maintain skin elasticity and suppleness10.
Our collagen is derived from fish scales. It solubilizes instantly in water: no cloudiness, odorless and tasteless.
Ceramide
Ceramides are natural lipids found in the skin. They play a specific structural and signaling role within the epidermis, helping to maintain its protective function by forming and reinforcing the skin barrier against many environmental factors such as sun exposure, oxidative stress and the natural aging process10.
Vitamin C
It helps improve skin health and appearance by enhancing collagen development and supporting natural defenses against UV radiation (sunlight) and induced skin damage. It is an essential coenzyme for endogenous collagen synthesis. That’s why it’s a natural choice for this type of formula. This vitamin could be extracted from plants such as acerola(Malpighia glabra L.) or rosehip(Rosa canina L.) 11.
Biotin
Biotin, or vitamin B8, helps maintain healthy skin by facilitating the proper functioning of the sebaceous glands. It also helps strengthen hair by promoting the production of keratin, an essential structural protein12.
