{"id":14779,"date":"2024-08-28T15:05:38","date_gmt":"2024-08-28T13:05:38","guid":{"rendered":"https:\/\/www.pharmanager-ingredients.com\/ingredients\/nattiase-for-normal-blood-circulation\/"},"modified":"2025-07-02T09:57:38","modified_gmt":"2025-07-02T07:57:38","slug":"nattiase-for-normal-blood-circulation","status":"publish","type":"ingredients","link":"https:\/\/www.pharmanager-ingredients.com\/en\/ingredients\/nattiase-for-normal-blood-circulation\/","title":{"rendered":"Nattiase: for normal blood flow."},"content":{"rendered":"<section id=\"block_d12fb33c9ebf5a445305ee252a8572bf\" class=\" section section_header-premium-block\">\n    <div class=\"header-premium-block_container container\">\n                        <div class=\"header-premium-logo-select\">\n                                                            \n<a href=\"?add-to-cart=14813\"\n         class=\"btn btn-add-cart ajax_toggle_cart_product added_to_cart header-premium-block btn-green btn-icon btn-select \"\n   data-quantity=\"1\" data-product_id=\"14813\"\n   data-cart_item_key=\"\"\n   data-product_name=\"NATTIASE - Fermented soy extract [20000-28000]FU\/g\"\n>\n    <span class=\"icon icon-add\"><\/span><\/a>                                                                                                <div class=\"premium-logo\">\n                        <img decoding=\"async\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/logo_\u6a19\u6e96\u8272.png\" alt=\"\"\/>\n                    <\/div>\n                            <\/div>\n            <h1 class=\"header-premium-title\">\n                Nattiase: for normal blood flow.            <\/h1>\n                            <p>Nattiase\u00a9 is a fermented soy extract whose active ingredient is nattokinase. It helps maintain a healthy balance of blood fluidity and circulation. <\/p>\n            \n                            <div class=\"header-premium-cta\">\n                                                                                <a href=\"#\" class=\"btn btn-green brochure-btn-modal\">\n                                    <span>Brochure request<\/span>\n                                <\/a>\n                                                                                        <a href=\"#\" class=\"btn btn-green fiche-btn-modal\">\n                                    <span>Request the data sheet<\/span>\n                                <\/a>\n                                                                                        <a href=\"#\" class=\"btn btn-green rdv-btn-modal\">\n                                    <span>Make an appointment for a presentation<\/span>\n                                <\/a>\n                                                                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id=\"lastname\" name=\"lastname\" placeholder=\"Name\" required>\n                        <\/div>\n                        <div class=\"form-group\">\n                            <input type=\"text\" id=\"firstname\" name=\"firstname\" placeholder=\"First name\" required>\n                        <\/div>\n                    <\/div>\n                    <div class=\"form-group-col2\">\n                        <div class=\"form-group\">\n                            <input type=\"text\" id=\"society\" name=\"society\" placeholder=\"Company\" required>\n                        <\/div>\n                        <div class=\"form-group\">\n                            <input type=\"text\" id=\"phone\" name=\"phone\" placeholder=\"N\u00b0 de t\u00e9l\u00e9phone\">\n                        <\/div>\n                    <\/div>\n                    <div class=\"form-group\">\n                        <input type=\"text\" id=\"email\" name=\"email\" placeholder=\"E-mail address\" required>\n                    <\/div>\n                    <div class=\"form-group-check\">\n                        <label>\n                            <input name=\"rgpd\" type=\"checkbox\" id=\"rgpd\" value=\"1\" required>\n                            <span class=\"checkbox\"><\/span>\n                            <span class=\"label\">J&#8217;accepte que Pharmanager Ingredients recueille mes donn\u00e9es personnelles et j&#8217;ai pris connaissance de la <a href=\"https:\/\/www.pharmanager-ingredients.com\/en\/privacy-policy\/\">politique de confidentialit\u00e9<\/a><\/span>\n                        <\/label>\n                    <\/div>\n                    <button type=\"submit\" class=\"btn btn-green\"><span>Send the request<\/span><\/button>\n                <\/form>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div><div id=\"ficheModal\" class=\"modal modal-ajax-form modal-fiche\">\n    <div class=\"modal-content\">\n        <div class=\"modal-close close\">\n            <span 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value=\"https:\/\/www.pharmanager-ingredients.com\/en\/wp-json\/wp\/v2\/ingredients\/14779\/\">\n\n                    <div class=\"form-ingredients\">\n                        <span class=\"form-group-label\"><strong>I would like to receive the :<\/strong><\/span>\n                        <template class=\"modal-checkbox-template\">\n                            <div class=\"form-group-check\">\n                                <label>\n                                    <input name=\"ingredient[]\" type=\"checkbox\" id=\"ingredient-\" value=\"1\">\n                                    <span class=\"checkbox\"><\/span>\n                                    <span class=\"label\"><\/span>\n                                <\/label>\n                            <\/div>\n                        <\/template>\n                        <div class=\"checkboxes\">\n                        <\/div>\n                    <\/div>\n                    <div class=\"form-group-col2\">\n                        <div class=\"form-group\">\n                            <input type=\"text\" id=\"lastname\" name=\"lastname\" placeholder=\"Name\"\n                                   required>\n                        <\/div>\n                        <div class=\"form-group\">\n                            <input type=\"text\" id=\"firstname\" name=\"firstname\" placeholder=\"First name\"\n                                   required>\n                        <\/div>\n                    <\/div>\n                    <div class=\"form-group-col2\">\n                        <div class=\"form-group\">\n                            <input type=\"text\" id=\"society\" name=\"society\" placeholder=\"Company\"\n                                   required>\n                        <\/div>\n                        <div class=\"form-group\">\n                            <input type=\"text\" id=\"phone\" name=\"phone\"\n                                   placeholder=\"Phone number\">\n                        <\/div>\n                    <\/div>\n                    <div class=\"form-group\">\n                        <input type=\"text\" id=\"email\" name=\"email\" placeholder=\"E-mail address\"\n                               required>\n                    <\/div>\n                    <div class=\"form-group-check\">\n                        <label>\n                            <input name=\"rgpd\" type=\"checkbox\" id=\"rgpd\" value=\"1\" required>\n                            <span class=\"checkbox\"><\/span>\n                            <span class=\"label\">J&#8217;accepte que Pharmanager Ingredients recueille mes donn\u00e9es personnelles et j&#8217;ai pris connaissance de la <a href=\"https:\/\/www.pharmanager-ingredients.com\/en\/privacy-policy\/\">politique de confidentialit\u00e9<\/a><\/span>\n                        <\/label>\n                    <\/div>\n                    <button type=\"submit\" class=\"btn btn-green\"><span>Send the request<\/span><\/button>\n                <\/form>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div><template id=\"validationModal\">\n    <p><strong>Thank you for your request.<\/strong><\/p>\n    <p>We&#8217;ll get back to you as soon as possible!<\/p>\n    <a href=\"#\" class=\"btn btn-green close\"><span>Continue on page<\/span><\/a>\n    <a href=\"https:\/\/www.pharmanager-ingredients.com\/en\/catalogue-ingredients-fonctionnels\/\" class=\"btn btn-green\"><span>View our catalog<\/span><\/a>\n<\/template><section id=\"block_fd9c7901a23b43689100fc34381c13ae\"\n         class=\" section section_list-block section_list-bg-color section_list-dynamic-height\"\n         style=\"background-color: #f7f7f7;\">\n    <div class=\"list-block_container container\">\n                    <div class=\"list-title\">\n                <h2>Why choose <span style=\"color: #473375;\">Nattiase\u00a9?<\/span><\/h2>\n            <\/div>\n        \n                    <div class=\"list-block_slider\">\n                                    <div class=\"list-item\">\n                        <div class=\"item-content\" style=\"background-color: #f7f7f7;\">\n                                                                                                                                                                        <img decoding=\"async\" alt=\"Nattiase - Nattokinase : icone coeur\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/icone-coeur.png\" class=\"image\" \/>\n                                                                                                                                                                        <p>Innovative ingredient for the cardiovascular system.<\/p>\n                                                                                    <\/div>\n                    <\/div>\n                                    <div class=\"list-item\">\n                        <div class=\"item-content\" style=\"background-color: #f7f7f7;\">\n                                                                                                                                                                        <img decoding=\"async\" alt=\"Nattiase - Nattokinase : icone dissolution fibrine\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/icone-dissolution-fibrine.png\" class=\"image\" \/>\n                                                                                                                                                                        <p>A mechanism of action on fibrin dissolution.<\/p>\n                                                                                    <\/div>\n                    <\/div>\n                                    <div class=\"list-item\">\n                        <div class=\"item-content\" style=\"background-color: #f7f7f7;\">\n                                                                                                                                                                        <img decoding=\"async\" alt=\"Nattiase - Nattokinase : icone conformit\u00e9 NF\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/conforme-NF.png\" class=\"image\" \/>\n                                                                                                                                                                        <p>Complies with European Novel Food regulations.<\/p>\n                                                                                    <\/div>\n                    <\/div>\n                                    <div class=\"list-item\">\n                        <div class=\"item-content\" style=\"background-color: #f7f7f7;\">\n                                                                                                                                                                        <img decoding=\"async\" alt=\"Nattiase - Nattokinase : icone application\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/icone-application-multiples.png\" class=\"image\" \/>\n                                                                                                                                                                        <p>Multiple cognitive and circulatory applications.<\/p>\n                                                                                    <\/div>\n                    <\/div>\n                            <\/div>\n            <\/div>\n<\/section><section id=\"block_9742a2cecf000d6a4bfe223121dadd48\" class=\" section section_content-block section_content-no-bg section_content-right-img\" >\n    <div class=\"content-block_container container\">\n                <div class=\"content-block_img\">\n            <img decoding=\"async\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/image-premium-nattiase.jpg\" alt=\"Nattiase - premium ingredients\"\/>\n        <\/div>\n                                                    <div class=\"content-block_content\">\n                                                        <h2>What is <span style=\"color: #473375;\">Nattiase\u00a9?<\/span><\/h2>\n<p style=\"text-align: justify;\">Nattiase\u00ae is a fermented soy extract containing an enzyme called nattokinase. This enzyme comes from the fermentation of soy by <i>Bacillus subtilis<\/i>. This fermented soybean is also known as &#8220;natto&#8221;, and the Japanese consume it regularly as a foodstuff thanks to its various nutritional virtues. Nattiase\u00ae, a source of nattokinase, is renowned for its beneficial effect on cardiovascular function, as it maintains good blood fluidity.   <\/p>\n                                                                    <\/div>\n                            <\/div>\n<\/section><section id=\"block_122c0cef8fa9e1f3454262a737c220a8\"\n         class=\" section section_list-block section_list-no-bg \"\n         >\n    <div class=\"list-block_container container\">\n                    <div class=\"list-title\">\n                <h2><span style=\"color: #473375;\">Production<\/span> stages<\/h2>\n<p style=\"text-align: justify;\">Nattiase produced by our partner Contek in Taiwan. This company specializes in the production of nattokinase. In 2019, Pharmanager Ingredients and Contek have joined forces to offer a nattokinase that fully meets the specifications of Novel Food Regulation 2015\/2283 and Implementing Regulation (EU) 2017\/2470. Nattiase is therefore the fruit of this partnership, with development to ensure regulatory compliance, but also and above all transpositions of specific analysis methods from Asia to our partner laboratories in France.   <\/p>\n            <\/div>\n        \n                    <div class=\"list-block_slider\">\n                                    <div class=\"list-item\">\n                        <div class=\"item-content\" style=\"background-color: #f7f7f7;\">\n                                                                                                                                                                        <img decoding=\"async\" alt=\"Nattiase - Nattokinase : icone soja\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/base-icone-soja.png\" class=\"image\" \/>\n                                                                                                                                                                        <p>Selection of raw materials<\/p>\n                                                                                    <\/div>\n                    <\/div>\n                                    <div class=\"list-item\">\n                        <div class=\"item-content\" style=\"background-color: #f7f7f7;\">\n                                                                                                                                                                        <img decoding=\"async\" alt=\"Nattiase - Nattokinase : icone inoculation\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/base-icone-inoculation-1.png\" class=\"image\" \/>\n                                                                                                                                                                        <p><strong>Pre-treatment<\/strong> Inoculation<\/p>\n                                                                                    <\/div>\n                    <\/div>\n                                    <div class=\"list-item\">\n                        <div class=\"item-content\" style=\"background-color: #f7f7f7;\">\n                                                                                                                                                                        <img decoding=\"async\" alt=\"Nattiase - Nattokinase : icone fermentation\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/base-icone-fermentation.png\" class=\"image\" \/>\n                                                                                                                                                                        <p><strong>Pre-treatment <\/strong>Fermentation<\/p>\n                                                                                    <\/div>\n                    <\/div>\n                                    <div class=\"list-item\">\n                        <div class=\"item-content\" style=\"background-color: #f7f7f7;\">\n                                                                                                                                                                        <img decoding=\"async\" alt=\"Nattiase - Nattokinase : icone purification\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/base-icone-purification-1.png\" class=\"image\" \/>\n                                                                                                                                                                        <p><strong>Production <\/strong>Purification<\/p>\n                                                                                    <\/div>\n                    <\/div>\n                                    <div class=\"list-item\">\n                        <div class=\"item-content\" style=\"background-color: #f7f7f7;\">\n                                                                                                                                                                        <img decoding=\"async\" alt=\"Nattiase - Nattokinase : mise en poudre\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/base-icone-Lyophilisation.png\" class=\"image\" \/>\n                                                                                                                                                                        <p><strong>Production <\/strong>Lyophilization<\/p>\n                                                                                    <\/div>\n                    <\/div>\n                                    <div class=\"list-item\">\n                        <div class=\"item-content\" style=\"background-color: #f7f7f7;\">\n                                                                                                                                                                        <img decoding=\"async\" alt=\"Nattiase - Nattokinase : mise en poudre\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/base-icone-miseEnPoudre.png\" class=\"image\" \/>\n                                                                                                                                                                        <p>Powder coating<\/p>\n                                                                                    <\/div>\n                    <\/div>\n                            <\/div>\n            <\/div>\n<\/section><section id=\"block_f8646f838ea0ce4c2170b0a58b4f80d5\" class=\" section section_content-block section_content-bg-color section_content-left-img\" style=\"background-color: #f7f7f7;\">\n    <div class=\"content-block_container container\">\n                <div class=\"content-block_img\">\n            <img decoding=\"async\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/19726.jpg\" alt=\"Nattiase - Nattokinase : usine\"\/>\n        <\/div>\n                                                    <div class=\"content-block_content\">\n                                                        <h2><span style=\"color: #473375;\">Quality control and production lines<\/span><\/h2>\n<p style=\"text-align: justify;\">Nattiase production takes place in ISO7-certified rooms on an ISO 22000 and FSSC 22000-certified site.<\/p>\n<p style=\"text-align: justify;\">This begins with a rigorous selection of the soybeans that will be the substrate for enzyme production. The industrial process follows two main stages: pre-treatment and production. <\/p>\n<p style=\"text-align: justify;\">We control the quality of Nattiase throughout the production chain. We analyze the batches produced according to the parameters defined in our specifications, in compliance with Novel Food regulation 2015\/2283. <\/p>\n<p style=\"text-align: justify;\">Finally, in vivo safety studies revealed no effects associated with the use of Nattiase. These included 28-day repeated-dose oral toxicity, acute toxicity and mutagenicity tests. <\/p>\n                                                                    <\/div>\n                            <\/div>\n<\/section><section\n        id=\"block_5a11a07bdab3aa1dac3252057c3ff72c\"\n        class=\" section section_idea-ingredient-block section_idea-ingredient-no-bg\"\n        >\n    <div class=\"idea-ingredient-block_container container\">\n                    <div class=\"idea-ingredient-title\">\n                <h2 style=\"text-align: center;\"><span style=\"color: #473375;\">Association ideas<\/span> by health area<\/h2>\n            <\/div>\n                <div class=\"idea-ingredient-select\">\n            <p>Select one or more axes:<\/p>\n            <div class=\"form-group-select\">\n                <div class=\"icon-wrapper\">\n                                        <span class=\"icon icon-favorite\"><\/span>\n                                    <\/div>\n                <select name=\"axe\" id=\"block_5a11a07bdab3aa1dac3252057c3ff72c-axe-select\">\n                    <option value=\"\" data-icon=\"ICAgICAgICAgICAgICAgICAgICA8c3BhbiBjbGFzcz0iaWNvbiBpY29uLWZhdm9yaXRlIj48L3NwYW4+CiAgICAgICAgICAgICAgICAgICAg\">All<\/option>\n                                            <option value=\"cholesterol\" data-axe=\"15016\" data-icon=\"PGltZyBzcmM9Imh0dHBzOi8vd3d3LnBoYXJtYW5hZ2VyLWluZ3JlZGllbnRzLmNvbS93cC1jb250ZW50L3VwbG9hZHMvMjAyNC8wNi9jaG9sZXN0ZXJvbC53ZWJwIiBhbHQ9IiIgd2lkdGg9IjEyNCIgaGVpZ2h0PSIxNjAiIGNsYXNzPSJhbGlnbmNlbnRlciBzaXplLW1lZGl1bSB3cC1pbWFnZS04MTY1IiAvPg==\">Cholest\u00e9rol<\/option>\n                                            <option value=\"circulation\" data-axe=\"\" data-icon=\"PGltZyBzcmM9Imh0dHBzOi8vd3d3LnBoYXJtYW5hZ2VyLWluZ3JlZGllbnRzLmNvbS93cC1jb250ZW50L3VwbG9hZHMvMjAyNC8wOS9CYXNlLXBvdWRyZS1uYXR0aWFzZS0xLTMwMHgzMDAucG5nIiBhbHQ9IiIgd2lkdGg9IjMwMCIgaGVpZ2h0PSIzMDAiIGNsYXNzPSJhbGlnbmNlbnRlciBzaXplLW1lZGl1bSB3cC1pbWFnZS0xMTQ5NSIgLz4=\">Circulation<\/option>\n                                            <option value=\"performance-sportive\" data-axe=\"\" data-icon=\"PGltZyBzcmM9Imh0dHBzOi8vd3d3LnBoYXJtYW5hZ2VyLWluZ3JlZGllbnRzLmNvbS93cC1jb250ZW50L3VwbG9hZHMvMjAyNC8wOS9CYXNlLXBvdWRyZS1uYXR0aWFzZS0xLTMwMHgzMDAucG5nIiBhbHQ9IiIgd2lkdGg9IjMwMCIgaGVpZ2h0PSIzMDAiIGNsYXNzPSJhbGlnbmNlbnRlciBzaXplLW1lZGl1bSB3cC1pbWFnZS0xMTQ5NSIgLz4=\">Performance sportive<\/option>\n                                            <option value=\"fonction-cognitive\" data-axe=\"\" data-icon=\"PGltZyBzcmM9Imh0dHBzOi8vd3d3LnBoYXJtYW5hZ2VyLWluZ3JlZGllbnRzLmNvbS93cC1jb250ZW50L3VwbG9hZHMvMjAyNC8wOS9CYXNlLXBvdWRyZS1uYXR0aWFzZS0xLTMwMHgzMDAucG5nIiBhbHQ9IiIgd2lkdGg9IjMwMCIgaGVpZ2h0PSIzMDAiIGNsYXNzPSJhbGlnbmNlbnRlciBzaXplLW1lZGl1bSB3cC1pbWFnZS0xMTQ5NSIgLz4=\">Fonction cognitive<\/option>\n                                    <\/select>\n            <\/div>\n        <\/div>\n        <div class=\"idea-ingredient-grid\">\n                                                    <a href=\"https:\/\/www.pharmanager-ingredients.com\/en\/ingredients\/artichoke-leaf\/\"\n                data-axe-cholesterol                data-layer-select-item=\"{&quot;item_name&quot;:&quot;ARTICHOKE&quot;,&quot;item_id&quot;:14203,&quot;price&quot;:0,&quot;item_list_name&quot;:&quot;default&quot;,&quot;item_list_id&quot;:0}\"\n    >\n        <div class=\"product\">\n           <img decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/artichok-powder-1.png\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"artichoke-leaf\" srcset=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/artichok-powder-1.png 500w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/artichok-powder-1-300x300.png 300w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/artichok-powder-1-150x150.png 150w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/artichok-powder-1-100x100.png 100w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>                        <h2 class=\"woocommerce-loop-product__title\">ARTICHOKE<\/h2>\n            <p class=\"product-latin-name\">Cynara scolymus L.<\/p>\n        <\/div>\n    <\/a>\n                                        <a href=\"https:\/\/www.pharmanager-ingredients.com\/en\/ingredients\/ginkgo-biloba-leaves\/\"\n                data-axe-circulation                data-layer-select-item=\"{&quot;item_name&quot;:&quot;GINKGO BILOBA&quot;,&quot;item_id&quot;:14718,&quot;price&quot;:0,&quot;item_list_name&quot;:&quot;default&quot;,&quot;item_list_id&quot;:0}\"\n    >\n        <div class=\"product\">\n           <img decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/ginkgo-biloba-feuilles-en-poudre.png\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"Ginkgo Biloba leaf powder\" srcset=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/ginkgo-biloba-feuilles-en-poudre.png 500w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/ginkgo-biloba-feuilles-en-poudre-300x300.png 300w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/ginkgo-biloba-feuilles-en-poudre-150x150.png 150w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/ginkgo-biloba-feuilles-en-poudre-100x100.png 100w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>                        <h2 class=\"woocommerce-loop-product__title\">GINKGO BILOBA<\/h2>\n            <p class=\"product-latin-name\">Ginkgo biloba<\/p>\n        <\/div>\n    <\/a>\n                                        <a href=\"https:\/\/www.pharmanager-ingredients.com\/en\/ingredients\/witch-hazel\/\"\n                data-axe-circulation                data-layer-select-item=\"{&quot;item_name&quot;:&quot;WITCH HAZEL&quot;,&quot;item_id&quot;:14722,&quot;price&quot;:0,&quot;item_list_name&quot;:&quot;default&quot;,&quot;item_list_id&quot;:0}\"\n    >\n        <div class=\"product\">\n           <img decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/hamamelis-feuille-poudre.png\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"witch hazel\" srcset=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/hamamelis-feuille-poudre.png 500w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/hamamelis-feuille-poudre-300x300.png 300w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/hamamelis-feuille-poudre-150x150.png 150w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/hamamelis-feuille-poudre-100x100.png 100w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>                        <h2 class=\"woocommerce-loop-product__title\">WITCH HAZEL<\/h2>\n            <p class=\"product-latin-name\">Hamamelis virginiana L.<\/p>\n        <\/div>\n    <\/a>\n                                        <a href=\"https:\/\/www.pharmanager-ingredients.com\/en\/ingredients\/red-vine\/\"\n                data-axe-circulation                data-layer-select-item=\"{&quot;item_name&quot;:&quot;RED VINE&quot;,&quot;item_id&quot;:14738,&quot;price&quot;:0,&quot;item_list_name&quot;:&quot;default&quot;,&quot;item_list_id&quot;:0}\"\n    >\n        <div class=\"product\">\n           <img decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/vigne-rouge-poudre.png\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"red vine powder\" srcset=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/vigne-rouge-poudre.png 500w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/vigne-rouge-poudre-300x300.png 300w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/vigne-rouge-poudre-150x150.png 150w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/vigne-rouge-poudre-100x100.png 100w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>                        <h2 class=\"woocommerce-loop-product__title\">RED VINE<\/h2>\n            <p class=\"product-latin-name\">Vitis vinifera L. var. tinctoria<\/p>\n        <\/div>\n    <\/a>\n                                        <a href=\"https:\/\/www.pharmanager-ingredients.com\/en\/ingredients\/green-coffee\/\"\n                data-axe-performance-sportive                data-layer-select-item=\"{&quot;item_name&quot;:&quot;GREEN COFFEE&quot;,&quot;item_id&quot;:14763,&quot;price&quot;:0,&quot;item_list_name&quot;:&quot;default&quot;,&quot;item_list_id&quot;:0}\"\n    >\n        <div class=\"product\">\n           <img decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/cafe-vert-en-poudre.png\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"green coffee bean powder\" srcset=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/cafe-vert-en-poudre.png 500w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/cafe-vert-en-poudre-300x300.png 300w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/cafe-vert-en-poudre-150x150.png 150w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/09\/cafe-vert-en-poudre-100x100.png 100w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>                        <h2 class=\"woocommerce-loop-product__title\">GREEN COFFEE<\/h2>\n            <p class=\"product-latin-name\">Coffea arabica L.<\/p>\n        <\/div>\n    <\/a>\n                                        <a href=\"https:\/\/www.pharmanager-ingredients.com\/en\/ingredients\/chili\/\"\n                data-axe-performance-sportive                data-layer-select-item=\"{&quot;item_name&quot;:&quot;CAPSICUM&quot;,&quot;item_id&quot;:14776,&quot;price&quot;:0,&quot;item_list_name&quot;:&quot;default&quot;,&quot;item_list_id&quot;:0}\"\n    >\n        <div class=\"product\">\n           <img decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-capsicum-annuum.png\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"Capsicum annuum\" srcset=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-capsicum-annuum.png 500w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-capsicum-annuum-300x300.png 300w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-capsicum-annuum-150x150.png 150w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-capsicum-annuum-100x100.png 100w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>                        <h2 class=\"woocommerce-loop-product__title\">CAPSICUM<\/h2>\n            <p class=\"product-latin-name\"><\/p>\n        <\/div>\n    <\/a>\n                                        <a href=\"https:\/\/www.pharmanager-ingredients.com\/en\/ingredients\/ginseng\/\"\n                data-axe-fonction-cognitive                data-layer-select-item=\"{&quot;item_name&quot;:&quot;GINSENG&quot;,&quot;item_id&quot;:14765,&quot;price&quot;:0,&quot;item_list_name&quot;:&quot;default&quot;,&quot;item_list_id&quot;:0}\"\n    >\n        <div class=\"product\">\n           <img decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-ginseng-racine-1.png\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"ginseng root powder\" srcset=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-ginseng-racine-1.png 500w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-ginseng-racine-1-300x300.png 300w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-ginseng-racine-1-150x150.png 150w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-ginseng-racine-1-100x100.png 100w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>                        <h2 class=\"woocommerce-loop-product__title\">GINSENG<\/h2>\n            <p class=\"product-latin-name\">Panax ginseng C.A. Meyer<\/p>\n        <\/div>\n    <\/a>\n                                        <a href=\"https:\/\/www.pharmanager-ingredients.com\/en\/ingredients\/guarana\/\"\n                data-axe-fonction-cognitive                data-layer-select-item=\"{&quot;item_name&quot;:&quot;GUARANA&quot;,&quot;item_id&quot;:14769,&quot;price&quot;:0,&quot;item_list_name&quot;:&quot;default&quot;,&quot;item_list_id&quot;:0}\"\n    >\n        <div class=\"product\">\n           <img decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-guarana-seed-2.png\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"\" srcset=\"https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-guarana-seed-2.png 500w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-guarana-seed-2-300x300.png 300w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-guarana-seed-2-150x150.png 150w, https:\/\/www.pharmanager-ingredients.com\/wp-content\/uploads\/2024\/08\/Base-poudre-guarana-seed-2-100x100.png 100w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>                        <h2 class=\"woocommerce-loop-product__title\">GUARANA<\/h2>\n            <p class=\"product-latin-name\">Paullinia cupana Kunth<\/p>\n        <\/div>\n    <\/a>\n                                    <\/div>\n            <\/div>\n<\/section><section id=\"histoire-rhodiola-rosea\" class=\" section section_accordion-block section_accordion-bg-color\" style=\"background-color: #f7f7f7;\">\n    <div class=\"accordion-block_container container\">\n                    <div class=\"accordion-title\">\n                <h2>A little <span style=\"color: #473375;\">science?<\/span><\/h2>\n            <\/div>\n        \n                    <div class=\"accordion-accordion\">\n                                    <div class=\"accordion_item\">\n                        <span class=\"accordion-title third-title\">\n                            Nattiase and hemostasis: an essential balance for blood circulation                            <span class=\"icon icon-keyboard_arrow_down\"><\/span>\n                        <\/span>\n                        <div class=\"accordion-content\">\n                            <p>The cardiovascular system distributes blood to all our organs. To ensure proper distribution of blood throughout the body, various physiological phenomena are put in place by our body. This is called hemostasis. This mechanism helps maintain a healthy balance in blood fluidity and circulation. This phenomenon brings together a number of complex physiological processes, including control of vessel motricity (vasoconstriction and vasodilatation), platelet aggregation and the synthesis of enzymes and plasma proteins such as fibrin, whose main role is to maintain proper blood coagulation. Once fibrin has fulfilled its role, it is naturally degraded by an enzyme called plasmin. Plasmin has the ability to destroy certain plasma proteins. This balance between coagulation and fluidity maintains blood circulation in normal conditions. Nattiase\u00ae is renowned for its beneficial effect on cardiovascular function, as it maintains good blood fluidity. Nattiase&#8217;s activity is also explained by its fibrin degradation mechanism: a mechanism similar to that of plasmin. This ensures normal blood circulation   <\/p>\n                        <\/div>\n                    <\/div>\n                                    <div class=\"accordion_item\">\n                        <span class=\"accordion-title third-title\">\n                            Nattokinase history and studies                            <span class=\"icon icon-keyboard_arrow_down\"><\/span>\n                        <\/span>\n                        <div class=\"accordion-content\">\n                            <p>Natto, a soy-based food fermented with <i>Bacillus subtilis<\/i> bacteria, has been part of Japanese cuisine<sup>1<\/sup> for over 1,000 years, appreciated for its gustatory qualities. Much more than a simple dish, natto is consumed for its various nutritional virtues<sup>2<\/sup>. This is perhaps one of the reasons why the Japanese enjoy a longer lifespan and better cardiovascular health than people in other countries<sup>3<\/sup>. Following the discovery of nattokinase in the early 80s by Dr Hiroyuki Sumi, many studies evaluated the health effects of supplementation with this enzyme, which has a molecular weight of 27.7 kDa and is made up of 275 amino acids. The results have been particularly interesting for the cardiovascular axis:  <\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>Normal circulation and blood flow. <sup>4<\/sup><\/li>\n<li>Improved lipid profile by increasing the level of good cholesterol in the blood (HDL). <sup>5<\/sup><\/li>\n<li>Normal blood pressure.  <sup>6-7<\/sup><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p style=\"text-align: justify;\">In the USA, nattokinase has been available for sale since 1998, and gained in popularity at the beginning of 2002 after the American population became aware of its health benefits, particularly with regard to the cardiovascular axis, as well as the media coverage of the benefits of the Asian diet (natto).<\/p>\n<p>&nbsp;<\/p>\n<p>Sources :<\/p>\n<p><sup>1. Kurosawa Y, Nirengi S, Homma T, Esaki K, Ohta M, Clark JF, Hamaoka T. Sci Rep. 2015 Jun 25;5:11601. doi: 10.1038\/srep11601. PMID: 26109079; PMCID: PMC4479826.<\/sup><br \/>\n<sup>2. Afzaal M, Saeed F, Islam F, Ateeq H, Asghar A, Shah YA, Ofoedu CE, Chacha JS.Biochem Res Int. 2022 Oct 21;2022:5863887. doi: 10.1155\/2022\/5863887. PMID: 36312453; PMCID: PMC9616652.<\/sup><br \/>\n<sup>3. \u00ab Mortalit\u00e9 due aux maladies cardiovasculaires \u00bb, dans Health at a Glance 2015 : OECD Indicators, \u00c9ditions OCDE, Paris.<\/sup><br \/>\n<sup>4.\tKurosawa, Yuko et al.  Scientific reports vol. 5 11601. 25 Jun. 2015<\/sup><br \/>\n<sup>5.\tRen NN, Chen HJ, Li Y, Mcgowan GW, Lin YG.  Zhonghua Yi Xue Za Zhi. 2017 Jul 11;97(26):2038-2042. Chinese. doi: 10.3760\/cma.j.issn.0376-2491.2017.26.005. PMID: 28763875.<\/sup><br \/>\n<sup>6.\tKim JY, Gum SN, Paik JK, Lim HH, Kim KC,  Hypertens Res. 2008 Aug;31(8):1583-8. doi: 10.1291\/hypres.31.1583. PMID : 18971533.<\/sup><br \/>\n<sup>7.\tJ Jensen GS, Lenninger M, Ero MP, Benson KF. Integr Blood Press Control. 2016 Oct 13;9:95-104. doi: 10.2147\/IBPC.S99553. <\/sup><\/p>\n                        <\/div>\n                    <\/div>\n                            <\/div>\n            <\/div>\n<\/section>","protected":false},"featured_media":11495,"menu_order":0,"template":"","meta":{"_acf_changed":true},"class_list":["post-14779","ingredients","type-ingredients","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Nattokinase - Nattiase\u00ae<\/title>\n<meta name=\"description\" content=\"Nattiase\u00ae: fermented soy extract qualified in nattokinase. 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